Anatomy Chapter 10

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which type of muscle tissue has the greatest effect on the body’s heat production?


sacromere is best defined as

a repeating unit of striated muscle

when a muscle contraction develops tension but doesn’t shorten the muscle, the contraction is called


skeletal muscle does each of these except

pump blood

muscle fatigue occurs due to a buildup of _______ and _____ in pH

lactic acid; decrease

which thick filament binds to actin once its active binding sites are exposed


all of the following are found in both skeletal and cardiac muscle fibers except

intercalated disks

the biochemical reaction that consumes the majority of a muscle’s ATP is the

actin myosin cross-bridge cycle

muscles are attached to bones by tendons or


a thin layer of connective tissue that surrounds a muscle fascicle is called the


the dense layer of connective tissue that surrounds the entire skeletal muscle is the


in a sacromere, thick filaments are linked laterally by proteins of the

M line

the advantage of having many nuclei in a skeletal muscle fiber is

the ability to produce large amounts of the muscle proteins needed for growth and repair

skeletal muscle fibers are formed from embryonic cells called


the plasma membrane of a skeletal muscle fiber is called the


muscle fibers differ from "typical cells" in that muscle fibers

have many nuclei

at rest, the tropomyosin muscle is held in place by

troponin molecules

at rest, active sites on the actin are blocked by

tropomyosin molecules

the series of membranous channels that surround each myofibril is the

sacroplasmic reticulum

when a skeletal muscle fiber contracts

the zones of overlap get lager, the h bands and i bands get smaller, zline gets closer together, width of a band remains constant

since each myofibril is attached at either end of the muscle fiber, when sacromeres shorten, the muscle fibers


the neuromuscular junction is a connection between a neuron and a

muscle fiber

the end of a neuron, where acetylcholine-filled vesicles are located is called the

synaptic terminal

what is the synaptic cleft

space between the synaptic terminal and the motor end plate

inside a neuron, acetylcholine is contained within


what causes the vesicle inside a neuron to fuse with the plasma membrane

an action potential in the neuron

acetylcholine receptors are primarily located

on motor end plate

an action potential in the muscle fiber causes

the muscle fibers to contract

the role of acetylcholinesterase in the neuromuscular junction is to

remove acetylcholine from the synaptic cleft

inside a muscle, bundles of single muscle fibers from


the muscle action potentials that initiate contraction are transmitted from the interior of the muscle fiber by

t tubules

t tubules and the terminal cistern are clustered into structures called


the sacroplasmic reticulum contains


which organelle completely surrounds each myofibril inside a muscle fiber

sacroplasmic reticulum

to what regulatory protein does calcium bind during the initiation of the contraction cycle in skeletal muscle fibers


which causes the active site of actin to be exposed or uncovered


which most correctly describes excitation in the context of excitation-contraction coupling in skeletal muscle

the generation of an action potential in the sacrolemma

which of the following phrases best decries how excitation is couples to contraction in skeletal muscle fibers

through calcium release from the sacroplasmic reticulum

MH is a rare genetic disease. which of the following best describes how anesthesia would affect the skeletal muscles of a patient with MH

the muscles would contract because of calcium binging to troponin

during neuromuscular transmission, the axon terminals release


the muscle action potential penetrates into a fiber along the

transverse tubules

in response to an action potential along the transverse tubules, the ____ release(s) calcium ions into the sacroplasm

sacroplasmic reticulum

the narrow space between the synaptic terminal and the muscle fibers is the

synaptic cleft

each skeletal muscle fiber is controlled by a motor neuron at a single

neuromuscular junction

active sites on the actin become available for binding after

calcium binds to troponin

receptors for acetylcholine are located on the

motor end plate

the action potential is conducted into a skeletal muscle fiber by

transverse tubules

the most important factor in decreasing the intracellular concentration of calcium ion after contraction is

active transport of calcium into the sacroplasmic reticulum

the calcium ion binds to troponin

tropomyosin moves into the groove between the helical actin strands

after death, muscle fibers run out of ATP and calcium begins to leak from the sacroplasmic reticulum into the sacroplasm resulting in a condition known as

rigor mortis

in sacromere, cross-bridge attachment occurs specifically in the

zone of overlap

triggering of the muscle action potential occurs after

acetylcholine binds to chemically-gated channels in the end plate membrane

how would the loss of acetylcholinesterase from the motor end plate affect skeletal muscle

it would cause spastic paralysis- muscles contract and unable to relax

when acetylcholine binds to receptors at the motor end plate, the end plate membrane becomes

more permeable to sodium ions

the cytoplasm of the neuromuscular terminal contain vesicles filed with molecules of the neurotransmitters


synaptic vesicles contain neurotransmitters that are released by ____ when the action potential arrives


the muscle weakness of myasthenia gravis results from

loss of acetylcholine receptors in the end-plate membrane

a patient takes a medication that clocks ACh receptors of skeletal muscle fibers. What is this drug’s effect on skeletal muscle contraction

reduced the muscle’s ability for contraction

to increase muscle tension, the nervous system can

increase stimulation frequency, recruit large motor units, increase the number of active motor units

the rapid rise and fall in force produced by a muscle fiber after a single action potential is

a twitch

a single motor neuron together with all the muscle fibers it innervates is called

a motor unit

in an isotonic contraction

muscle tension exceeds the load and the muscle lifts the load

anaerobic glycolysis provides energy for muscle contraction when the supply of __ is limited


during the core cycle, in the liver

glucose is produced from lactic acid

during the recovery period the body’s need for oxygen is increased because

additional oxygen is required to restore energy reserves consumed during exercise

a resting muscle generates most of its ATP by

aerobic metabolism of fatty acids

creatine phosphate

acts as an energy reserve in muscle tissue

during anaerobic glycolysis

oxygen is not consumed, pyretic acid and ATP produced, carbohydrate is metabolized

after heavy exercise, if energy reserves in a muscle are depleted, ___ occurs

an oxygen debt

which would lead to increased oxygen comsuption

all of the above

the ___ type of muscle fiber has relatively few mitochondria


type of muscle fiber that is most resistant to fatigue is the ___ fiber


fast fibers

have low resistance to fatigue and have quick twitches

fast muscle fibers can adapt to aerobic metabolism by generating more mitochondria in response to

repeated, exhaustive stimulation

slow muscle fibers compared to fast muscle fibers

generate less tension, rich in red protein myoglobin, take 3x as long to reach peak tension, have smaller fiber diameters

which is true about cardiac muscle fibers

single nucleus, have long twitch duration compared to skeletal fibers, fibers branch

ability of smooth muscle to function over a wide range of lengths is called


what is not a characteristic of smooth muscle

s. muscle connective tissue forms tendons and aponeuroses

which is not a function of smooth muscle tissue

forcing blood from heart into major arteries

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