Which of the following most clearly illustrates Russell and Burch’s Replacement concept? |
The use of computer modeling software instead of using animals in an experiment. |
What is the primary purpose of the "3Rs" concept from Russell and Burch? |
To decrease the use of animals in research and to minimize pain and distress caused by animal experiments. |
Which of the following most accurately describes the process that must occur when working with research animals covered by U.S. federal regulations? |
The research team must obtain IACUC approval for the proposed research procedures prior to starting the work. |
Which of the following is true regarding the use of animals in research? |
The attending veterinarian must be allowed to have access to all research animals at all times. |
Which of the following is the general guideline that IACUCs use to evaluate the potential pain of a procedure conducted with animals? |
Any procedure that causes pain or distress in human beings may cause pain or distress in other animals. |
Which entity is responsible for monitoring institutional compliance with PHS Policy? |
The Office of Laboratory Animal Welfare (OLAW) |
Which justification would an IACUC most likely accept if a research team plans to withhold pain relief (analgesia) from animals during a project? |
Documented evidence that the analgesic agent will interfere with the aims of the project. |
Prior to implementing any significant change in the use of animals, what is the most important thing that the research team must do? |
Obtain IACUC approval for the change. |
CITI RCR- Using Animals In Research
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