chap 7

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the CNS depressants include various prescription drugs referred to as

sedative-hypnotics

which of these is not one of the early sedative-hypnotics used in medicine?
chloral hydrate, paraldehyde, butyrate, bromide salts

butyrate

what has kept paraldehyde from being widely used

bad taste and odor

how are barbiturates usually classified

duration of action

among barbiturates, when prescribing a sleeping pill, physicians would chose a

higher dose of a shorter acting drug

2 drugs that were introduced as being safer that barbiturates, but in the long run proved to not be much safer were

meprobamate and methaqualone

the major advantage of benzodiazepines over barbiturates seems to be the

greater safety margin

Librium and valium were the first widely sold

benzodiazepines

the "date rape" drug Rohypnol

is sold as a hypnotic agent in many countries other than the US

when benzodiazepines bind to their receptor site, they

enhance the inhibitory effects of GABA

Ambien is

not a benzodiazepine chemically, but has similar effects

the four most widely sold benzodiazepines are all longer acting drugs sold primarily as

anxiolytics

sedative- hypnotic agents bind to which receptors in the brain?

GABA

animal self admin experiments and studies of drug choice among humans indicate that

short acting barbiturates are more likely to lead to dependence than any benzodiazepines

withdrawal from long term use of sedative hypnotic drugs us characterized by

anxiety, impaired concentration, insomnia, convulsions

one of the most dangerous acute effects of taking depressants in combination with alcohol is

respiratory depression

which of the following drugs could theoretically be used to treat barbiturate withdrawal?
meth, fluoxetine, alcohol, modafinil

alcohol

one of the oldest gaseous anesthetics, populary known as laughing gas is

nitrous oxide

what household product contains nitrous oxide

whipped cream

the modern era of abuse of volatile solvent by young people can be traced to a 1959 newspaper report of

glue sniffing

inhalant use has traditionally been more common among

poor hispanic and native american youth

GHB occurs

naturally in the brain

the usual recreation dose of GHB when taken alone is about

1-5 grams

anecdotally, _____ are used to enhance sexual pleasure

amyl nitrite

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