1) The term "gene expression" refers to the |
D) process by which genetic information flows from genes to proteins. |
2) A gene operon consists of |
D) transcribed genes, an operator, and a promoter. |
3) In a prokaryote, a group of genes with related functions, along with their associated control sequences, defines |
A) an operon. |
4) The lac operon in E. coli |
C) prevents lactose-utilizing enzymes from being expressed when lactose is absent from the environment. |
5) Proteins that bind to DNA and turn on operons by making it easier for RNA polymerase to bind to a promoter are called |
D) activators. |
6) The lac operon of E. coli is ________ when the repressor is bound to lactose. |
A) active |
7) The expression of the tryptophan operon is controlled by |
D) a repressor that is active when it binds to tryptophan. |
8) Which of the following is likely to occur in E. coli cells that are grown in skim milk? |
D) The trp repressor is activated and the cells will produce lactose-utilizing enzymes. |
9) A single cell, the zygote, can develop into an entirely new organism with many different specialized cells. Which of the following statements about this process is false? |
B) Additional genetic information for the formation of specialized cells is passed on to the developing embryo via the placenta. |
10) The basis of cellular differentiation is |
A) selective gene expression. |
11) The genes for the enzymes of glycolysis |
A) are active in all metabolizing cells, but the genes for specialized proteins are expressed only in particular cell types. |
12) Which of the following statements regarding DNA packing is false? |
C) DNA packing tends to promote gene expression. |
13) The relationship between DNA and chromosomes is most like |
B) thread wrapped around a spool. |
14) In female mammals, the inactive X chromosome in each cell |
B) becomes a Barr body. |
15) The tortoiseshell pattern on a cat |
B) results from X chromosome inactivation. |
16) Both prokaryotic and eukaryotic cells use ________ to turn certain genes on or off. |
D) proteins |
17) Enhancers are |
A) DNA sequences to which activator proteins bind. |
18) Silencers |
C) bind to DNA sequences and inhibit the start of transcription. |
19) RNA splicing involves the |
A) removal of introns from the molecule. |
20) The coding regions of a gene (the portions that are expressed as polypeptide sequences) are called |
B) exons. |
21) Which of the following permits a single gene to code for more than one polypeptide? |
C) alternative RNA splicing |
22) Small pieces of RNA that can regulate translation of mRNA are called |
B) microRNA. |
23) miRNA can be used by |
B) cells to prevent infections from double-stranded RNA viruses. |
24) All of the following mechanisms are used to regulate protein production except |
C) DNA editing. |
25) Which of the following mechanisms of controlling gene expression occurs outside of the nucleus? |
D) translation |
26) Which of the following statements about fruit fly development is false? |
D) The location of the head and tail ends of the egg is primarily determined by the location of sperm entry during fertilization. |
27) A homeotic gene |
A) serves as a master control gene that functions during embryonic development by controlling the developmental fate of groups of cells. |
28) Which of the following statements about microarrays is false? |
A) Microarrays use tiny portions of double-stranded RNA fragments from a large number of genes. |
29) In multicellular organisms, the coordination of cellular activities relies on |
A) cell-to-cell signaling and signal transduction pathways. |
30) To initiate a signal transduction pathway, a signal binds to a receptor protein usually located in the |
C) plasma membrane. |
31) Transcription factors attach to |
D) DNA. |
32) A signal outside a cell triggers changes in the transcription and translation inside the cell through |
B) signal transduction pathways. |
33) Yeast are able to communicate with each other |
B) through chemical signaling. |
34) Signal transduction pathways |
A) are mechanisms of communication that probably evolved in ancient prokaryotes. |
35) In plants, most differentiated cells retain |
C) a complete set of their genes, and retain the ability to express those genes under certain circumstances. |
36) Why can some plants be cloned from a single cell? |
D) Plant cells can dedifferentiate and give rise to all of the specialized cells required to produce an entire plant. |
37) Which of the following processes occurs when a salamander regenerates a lost limb? |
A) Certain cells in the limb dedifferentiate, divide, and then redifferentiate to form a new limb. |
38) The cloning of Dolly the sheep |
D) demonstrated that the nuclei from differentiated mammalian cells can retain their full genetic potential. |
39) The use of cloning to produce special embryonic stem cells is called |
B) therapeutic cloning. |
40) Which of the following mammals has not yet been cloned and brought through the complete gestation cycle? |
A) human |
41) Which of the following possible uses of reproductive cloning is still considered by most to be an unresolved ethical issue? |
A) the reproductive cloning of humans |
42) Which of the following statements regarding stem cells is false? |
B) Adult, but not embryonic, stem cells can be grown in laboratory culture. |
43) Adult stem cells have limited therapeutic potential |
B) because their developmental potential is limited to certain tissues. |
44) A gene that can cause cancer when present in a single copy in a cell is called a(n) |
A) oncogene. |
45) Which of the following statements about proto-oncogenes is false? |
B) A mutation in a tumor-suppressor gene can stop cell division immediately. |
46) Which of the following is not a factor that contributes to normal cells becoming cancerous? |
D) one or more of the cell’s genes being removed by a virus |
47) Cancer of the colon is caused by |
D) several somatic cell mutations. |
48) The development of colon cancer occurs slowly, and colon cancer is more frequently seen in the elderly than the young. This is most likely because |
C) four or more somatic mutations must occur to give rise to the cancer, which takes time. |
49) Mutations in the proto-oncogene ras and the tumor suppressor gene p53 |
B) disrupt normal regulation of the cell cycle. |
50) Mutations in the p53 gene can lead to cancer by |
A) causing the production of a faulty protein that is no longer able to inhibit cell division. |
51) The carcinogen known to cause the most cases and types of cancer is |
A) tobacco. |
52) Which of the following statements regarding cancer risk factors is false? |
D) Mutagens are usually not carcinogens. |
53) In this drawing of the lac operon, which molecule is an inactive repressor? |
D) molecule D |
54) Which structure in this figure shows one complete nucleosome? |
D) structure D |
55) Why don’t the grafted hybrids produce apples with a blend of traits from the scion and the rootstock? |
D) The rootstock regulates gene expression in the scion, but contributes no genetic information for fruit production. |
56) Half the trees in an orchard were derived from rootstock "A" and half from rootstock "B," but all the |
A) would be very likely to become infected, because the remaining scions are genetically identical to those that are already infected. |
mRNA can be used by |
Cells to prevent infections from double-stranded RNA viruses. |
Biology Chapter 11
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