Biology Chapter 10

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Which of the following build(s) new strands of DNA?

-DNA polymerases
-The lagging strand
-The leading strand
-Parental DNA
-The origins of replication

DNA polymerases DNA polymerases build new strands of DNA by adding DNA nucleotides one at a time.

Which statement about DNA replication is CORRECT?

-The leading strand is built continuously, and the lagging strand is built in pieces.

-DNA ligase helps assemble the leading strand.

-The lagging strand is one of the strands of parental DNA.

-The lagging strand is built continuously.

-The leading strand is one of the strands of parental DNA.

The leading strand is built continuously, and the lagging strand is built in pieces The leading and lagging strands are the new strands of DNA made during DNA replication. The leading strand is built continuously, and the lagging strand is built in pieces.

During DNA replication, which nucleotide will bind to an A nucleotide in the parental DNA?

G
C
T
A
U

T During DNA replication, A binds with T.

The molecule that seals the gaps between the pieces of DNA in the lagging strand is

-DNA ligase.

-DNA polymerase.

-RNA.

-the replication fork.

-the leading strand

DNA ligase DNA ligase seals the gaps between the pieces of DNA in the lagging strand, turning it into a continuous strand.

Which statement about DNA replication is FALSE?

-The two strands of parental DNA are separated during DNA replication.

-DNA ligase adds nucleotides to the lagging strand.

-DNA polymerase builds a new strand by adding DNA nucleotides one at a time.

-Because the two strands of parental DNA run in opposite directions, the new strands must be made in different ways.

-The lagging strand is made of a series of pieces that must be joined together to make a continuous strand.

DNA ligase adds nucleotides to the lagging strand. You’re right! This statement is FALSE. DNA ligase seals the gaps between segments of DNA in the lagging strand. It does not add nucleotides to the lagging strand.

The influenza virus, a deadly infectious agent found around the world, is composed of _____ and _____.

-DNA … RNA
-nucleic acid … RNA
-DNA … protein
-RNA … protein

RNA….Protein The influenza virus contains RNA surrounded by a protein coat

What do DNA and RNA have in common?

-Both contain deoxyribose.
-Both are composed of nucleotides.
-Both form double helices.
-They are composed of the same nucleotides.

both are composed of nucleotides. Both molecules are polymers built from nucleotide monomers.

The DNA polynucleotide structure contains which one of the following?

-peptide bonds
-adenine, guanine, cytosine, and thymine
-ribose
-sulfur

adenine, guanine, cytosine, and thymine A, G, C, and T are the four nitrogenous bases in DNA.

The most important aspect of Watson and Crick’s discovery of the structure of DNA was that it __________.

-described a mechanism for formation of all biological molecules
-helped explain how cells divide to form identical daughter cells
-provided a model for our understanding of cell structure
-described a role for nitrogen in biological molecules

helped explain how cells divide to form identical daughter cells It explained a copying mechanism for our genetic material

One strand of DNA serves as a template for the synthesis of another so that __________.

-DNA can serve as a template for the synthesis of other polymers

-there are two copies of each gene on a single DNA molecule

-the helical shape of DNA is conserved

-the progeny of each cellular replication gets the same genetic information

the progeny of each cellular replication gets the same genetic information After the double-stranded DNA molecule splits into two strands, each serves as a template for the synthesis of a complementary strand.

The backbone of DNA consists of ______.

a repeating sugar-phosphate-sugar-phosphate pattern

paired nucleotides

a repeating sugar-nucleotide-sugar-nucleotide pattern

nitrogenous bases

a repeating sugar-phosphate-sugar-phosphate pattern

Thymine and cytosine differ from adenine and guanine in that

thymine and cytosine are larger nitrogenous bases.

thymine and cytosine are only found in DNA, whereas adenine and guanine are only found in RNA.

thymine and cytosine are only found in DNA, whereas adenine and guanine are found in both DNA and RNA.

thymine and cytosine are single-ring structures, whereas adenine and guanine are double-ring structures.

thymine and cytosine are single-ring structures, whereas adenine and guanine are double-ring structures.

RNA contains the nitrogenous base ______ instead of ______, which is only found in DNA.

uracil… guanine

uracil… thymine

thymine… uracil

a deoxyribose sugar… a ribose sugar

uracil….thymine

If adenine makes up 20% of the bases in a DNA double helix, what percent of the bases are guanine?

30%
40%
20%
60%

30%

In a DNA double helix, adenine pairs with ______ and guanine pairs with ______.

thymine… cytosine

cytosine… thymine

uracil… cytosine

guanine… adenine

thymine…cytosine

If one strand of a DNA double helix has the sequence GTCCAT, what is the sequence of the other strand?

TGAACG
CAGGTA
CAGGUA
ACTTGC

CAGGTA

What type of chemical bond joins the bases of complementary DNA strands?

hydrogen
hydrophilic
ionic
covalent

hydrogen

After replication_____

each new DNA double helix consists of two new strands

one new DNA double helix consists of two old strands and the other new DNA double helix consists of two new strands

each new DNA double helix consists of one old strand and one new strand

each new DNA double helix consists of two old strands

each new DNA double helix consists of one old strand and one new strand

Which of the following events occurs during transcription?

A cap is added to the RNA molecule.

A molecule of RNA is formed based on the sequence of nucleotides in DNA.

Those segments of the RNA strand that do not actually code for the protein are removed.

mRNA binds to a ribosome in the cytoplasm.

The message in mRNA is translated into a protein.

A molecule of RNA is formed based on the sequence of nucleotides in DNA. During transcription, RNA nucleotides line up with their complementary DNA partners, transcribing the information in DNA into RNA.

Which of the following is a correct statement about mRNA?

mRNA moves from the nucleus to the cytoplasm following RNA processing.

Segments of mRNA that code for protein are removed before translation.

mRNA binds directly to amino acids during translation.

mRNA is transcribed from DNA in the cytoplasm.

mRNA includes a cap that consists of extra adenine nucleotides.

mRNA moves from the nucleus to the cytoplasm following RNA processing. mRNA undergoes RNA processing in the nucleus and then moves to the cytoplasm for translation.

The site of translation is

ribosomes in the cell nucleus.

ribosomes in the cell cytoplasm.

the cell nucleus.

the Golgi apparatus.

the plasma membrane.

ribosomes in the cell cytoplasm. Translation occurs at ribosomes in the cell cytoplasm.

Which one of the following does not play a role in translation?

Anticodon
tRNA
Ribosomes
DNA
Amino acids

DNA DNA contains the instructions for making proteins, but these instructions are transcribed to RNA before translation occurs.

Which of the following does not occur during RNA processing?

Segments of RNA that do code for the protein are reconnected.

Segments of the RNA strand that do not actually code for the protein are removed.

A modified guanine nucleotide is added to the beginning of the RNA strand as a cap.

Adenine nucleotides are added to the end of the RNA strand, forming a tail.

mRNA attaches to the small subunit of a ribosome.

mRNA attaches to the small subunit of a ribosome. mRNA attaches to the small subunit of a ribosome at the beginning of translation.

Beadle and Tatum discovered that each mutant mold they observed lacked a specific enzyme. As a result, they concluded that __________.

cells need specific enzymes to function

mutations are changes in genetic information

genes carry information for making proteins

genes are made of DNA

genes carry information for making proteins From their experiments with Neurospora crassa, they developed the one gene-one enzyme hypothesis.

The information carried by a DNA molecule is in __________.

the order of the nucleotides in the molecule

its amino acid sequence

the sugars and phosphates forming its backbone

the total number of nucleotides it contains

the order of the nucleotides in the molecule Genetic information resides in the order of the nucleotides on a DNA molecule.

Early geneticists wondered how only four nucleotides can specify the sequence of 20 amino acids in proteins. They hypothesized that there must be a code that linked the nucleotide sequence in a gene to the amino acid sequence in a protein. Each nucleotide code is called a codon. Today we know that there is a genetic code in which __________nucleotide(s) code(s) for each amino acid.

3
4
1
2

3 The number of possible 3-letter codes is 43 or 64. This is more than the number of amino acids. Thus, the code can be redundant. In some cases, there is more than one codon that codes for the same amino acid.

How does RNA polymerase know where to start transcribing a gene into mRNA?

RNA polymerase starts when the enzyme attaches to a certain nucleotide sequence called a promoter at the beginning of a gene.

Transfer RNA acts to translate the message to RNA polymerase.

The ribosome directs it to the correct portion of the DNA molecule.

It starts at one end of the chromosome.

RNA polymerase starts when the enzyme attaches to a certain nucleotide sequence called a promoter at the beginning of a gene. RNA polymerase binds to a gene’s promoter to initiate mRNA synthesis.

After an RNA molecule is transcribed from a eukaryotic gene, portions called _____ are removed and the remaining _____ are spliced together to produce an mRNA molecule with a continuous coding sequence.

promoters … terminators

codons … anticodons

caps … tails

introns … exons

inrons…exons Introns, intervening or noncoding sequences, are removed, and the exons, the expressed sequences, are spliced together.

The anticodon of an incoming _____ molecule, carrying its amino acid, pairs with the mRNA _____ at the ribosome.

ribosome … protein

amino acid … structure

tRNA … codon

tRNA … phosphates

tRNA … codon The codon-anticodon interaction positions an amino acid in the correct location in the growing polypeptide.

Which of the following processes occurs in the cytoplasm of a eukaryotic cell?

translation

RNA processing, including adding a cap and a tail

transcription

DNA replication

translation Translation takes place at ribosomes, which are found in the cytoplasm.

Which one of the following choices is true of tRNA?

Each tRNA binds a specific amino acid.

There are four types of tRNA.

tRNAs carry special sequences known as codons.

tRNAs are extremely small molecules.

Each tRNA binds a specific amino acid. A tRNA with a particular codon will bind to a specific amino acid and transfer it to the ribosome for insertion into the new polypeptide.

Which of the following are the three phases of translation?

addition of cap and tail, removal of exons, and RNA splicing

initiation, elongation, and completion

initiation, elongation, and termination

activation, chain growth, and completion

initiation, elongation, and termination These terms apply to both transcription and translation.

The flow of information in a cell proceeds __________.

from RNA to DNA to protein

from DNA to RNA to protein

from the cytoplasm to the nucleus

from the environment to DNA

from DNA to RNA to protein Transcription precedes translation.a change in the nucleotide sequence of DNA

A mutation is __________.

a mistake that can occur in either transcription or translation

a change in the nucleotide sequence of DNA

a temporary and reversible alteration in a DNA molecule

blockage of the ribosome-binding sites

a change in the nucleotide sequence of DNA Mutations are changes in the nucleotide sequence in the chromosomes.

The modern phrasing of Beadle and Tatum’s hypothesis about relationships between genes and their products is "one gene-one ______."

protein
enzyme
RNA
polypeptide

polypeptide

How many amino acids are common to all living systems?

10
20
30
100

20

How many nucleotides make up a codon?

2
3
4
5

3

The shared genetic code of all life on Earth is evidence that ______.

the genetic code arose relatively late in the history of life on Earth

bacterial cells arose earlier than eukaryotic cells

all life shares a common ancestry

DNA replication is error-free

all life shares a common ancestry

Transcription is the ______.

manufacture of two new DNA double helices that are identical to an old DNA double helix

manufacture of a protein based on information carried by RNA

modification of a strand of RNA prior to the manufacture of a protein

manufacture of a strand of RNA complementary to a strand of DNA

manufacture of a strand of RNA complementary to a strand of DNA

If a strand of DNA has the sequence AAGCTC, transcription will result in a(n) ______.

DNA double helix with the sequence AAGCTC for one strand and TTCGAG for the complementary strand

RNA double helix with the sequence UUCGAG for one strand and AAGCUC for the complimentary strand

single RNA strand with the sequence UUCGAG

single RNA strand with the sequence TTCGAG

single RNA strand with the sequence UUCGAG

Which of the following enzymes is responsible for RNA synthesis?

RNA ligase
RNA helicase
RNase
RNA polymerase

RNA polymerase

The absence of a terminator in transcription will result in ______.

the production of a longer RNA molecule

a strand of mRNA that lacks its cap and tail

the production of a shorter RNA molecule

the creation of a virus

the production of a longer RNA molecule

The correct sequence of events occurring during transcription is ______.

elongation, initiation, termination

initiation, elongation, termination

splicing, capping, tailing

tailing, capping, splicing

initiation, elongation, termination

The expressed (coding) regions of eukaryotic genes are called ______.

promoters
exons
caps
introns

exons

What protects mRNA from attack by cellular enzymes?

a cap and tail

RNA splicing

the removal of exons

the lack of RNA-digesting enzymes in the cytoplasm

a cap and tail

Translation converts the information stored in ______ to ______.

DNA… a polypeptide

DNA… RNA

RNA… a polypeptide

RNA… DNA

RNA…DNA

The DNA codon AGT codes for an amino acid carried by a tRNA with the anticodon ______.

AGU
TCU
TCA
AGT

AGU

During translation, what is the correct order of events that occur as an amino acid is added?

initiation, codon recognition, termination

translocation, codon recognition, termination

peptide bond formation, translocation, codon recognition

codon recognition, peptide bond formation, translocation

codon recognition, peptide bond formation, translocation

Peptide bonds form between ______.

an mRNA codon and a tRNA anticodon

an mRNA transcript and the small ribosomal subunit

amino acids

a tRNA and the amino acid it is carrying

amino acids

A mutation within a gene that will insert a premature stop codon in mRNA would ______.

change the location at which transcription of the next gene begins

have the same effect as deleting a single nucleotide in the gene

result in a shortened polypeptide chain

result in a polypeptide that is one amino acid shorter than the one produced prior to the mutation

result in a shortened polypeptide chain

What is the ultimate source of all diversity?

mutation
sexual recombination
natural selection
meiosis

sexual recombination

The figure below shows the flow of genetic information in a eukaryotic cell. The transfer of information from DNA into an RNA molecule is known as ______.

translation
transcription
polypeptide
DNA replication

transcription

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