Substance Abuse Chapter 7 Study Questions

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The CNS depressants include various prescription drugs referred to as…

sedative hypnotics

Which of these is NOT one of the early sedative-hypnotics used in medicine?

-chloral hydrate
-bromide salts

bromide salts

What has kept paraldehyde from being widely used?

bad taste and odor

How are barbiturates usually classified?

duration of action

Among the barbiturates, when prescribing a sleeping pill (hypnotic), physicians would usually choose a…

higher dose of a short-acting drug

Two drugs that were introduced as being safer than barbiturates, but in the long run proved to be not much safer, were…

meprobamate and methaqualone

The major advantage of the benzodiazepines over the barbiturates seems to be the…

greater safety margin

Librium (chlordiazepoxide) and Valium (diazepam) were the first widely sold…


The "date-rape" drug Rohypnol (flunitrazepam)…

is sold as a hypnotic agent (sleeping pill) in many countries other than the U.S.

When benzodiazepines bind to their receptor site, they…

enhance the inhibitory effects of GABA

Zolpidem (Ambien) is…

not a benzodiazepine chemically, but it has similar effects

The four most widely sold benzodiazepines are all longer-acting drugs sold primarily as…


Sedative-hypnotic agents bind to which receptors in the brain?


Animal self-administration experiments and studies of drug choice among humans indicate that…

short-acting barbiturates are more likely to lead to dependence than any of the benzodiazepines

Withdrawal from long-term use of sedative-hypnotic drugs is characterized by…

anxiety, insomnia, nausea, seizures

One of the most dangerous acute effects of taking depressants in combination with alcohol is…

respiratory depression

Which of the following drugs could theoretically be used to treat barbiturate withdrawal?


One of the oldest gaseous anesthetics, popularly known as "laughing gas" is…

nitrous oxide

What household product contains nitrous oxide?

whipped cream dispensers

The modern era of abuse of volatile solvents by young people can be traced to a 1959 newspaper report of …

glue sniffing

Inhalant use has traditionally been more common among…

poor Hispanic and Native American youth

GHB (gamma hydroxybutyric acid)…

occurs naturally in the brain

The usual recreational dose of GHB when taken alone is about…

1-5 grams

Anecdotally, _____ (or poppers) are used to enhance sexual pleasure.

amyl nitirite

T or F: Paraldehyde is a CNS depressant that is currently available in several over-the-counter medications.


T or F: When barbiturates were the most popular sedative-hypnotics, low doses of the long-acting types were used as sleeping pills.


T or F: Benzodiazepines replaced barbiturates primarily because they were believed to be safer.


T or F: Ambien (zolpidem) is a popular benzodiazepine used to treat anxiety.


T or F: Sodium pentathol is a long-acting barbiturate used to treat insomnia.


T or F: Among the sedative-hypnotic drugs, short-acting barbiturates seem to be the most likely to lead to drug dependence.


T or F: Nitrous oxide (laughing gas) is a schedule 1 controlled substance.


T or F: The majority of "huffers" (users of inhalants) are above age.


T or F: Volatile solvents that act as CNS depressants are found in a wide variety of houshold products.


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