In life-threatening starvation, the kidneys synthesize glucose by A. secreting erythropoietin |
deaminating amino acids. |
This byproduct of protein catabolism constitutes approximately one-half of all nitrogenous waste. A. urea |
urea |
Which organ system does not excrete waste? A. the urinary system |
the cardiovascular system |
Which is not a function of the kidneys? A. They regulate osmolarity of the body fluids. |
They release waste into the bloodstream. |
Which of the following is not an organ of the urinary system? A. urethra |
collecting duct |
A patient enters a hospital after a motorcycle accident. He complains of mid-back pain. X-rays reveal both rib and pelvic fractures. His emergency room examination includes urinalysis. Which of the following findings from the urinalysis would most likely suggest trauma to the kidneys from the accident, but not to the urinary bladder? A. pyuria |
albuminuria |
The innermost connective tissue layer protecting the kidney and assisting in staving off infection is known as A. the perirenal fat capsule. |
the fibrous capsule. |
A single lobe of a kidney is comprised of A. two calyces and a renal pelvis. |
one pyramid and the overlying cortex |
A renal pyramid voids urine into A. the minor calyx. |
the minor calyx. |
Which of these correctly traces blood flow from the renal artery into the renal cortex? A. arcuate a. → interlobar a. → afferent arteriole → interlobular a. |
segmental a. → interlobar a. → arcuate a. → interlobular a. |
The transition from an afferent arteriole to an efferent arteriole occurs in the A. glomerulus. |
glomerulus. |
The average person has approximately _______ nephrons per kidney. A. 1.2 million |
1.2 million |
Which of these correctly traces blood flow from the renal cortex to the renal vein? A. interlobular v. → interlobar v. → segmental v. → renal v. |
interlobular v. → arcuate v. → interlobar v. → renal v. |
Blood plasma is filtered in A. the renal tubule. |
the renal tubule. |
Which of these form the inner layer of the glomerular capsule and wrap around the capillaries of the glomerulus? A. macula densa cell |
podocytes |
All of the following are composed of cuboidal epithelium with the exception of A. the thin segment of the nephron loop. |
the thin segment of the nephron loop. |
Which are primarily responsible for maintaining the salinity gradient of the renal medulla? A. cortical nephrons |
juxtamedullary nephrons |
In the nephron, the fluid that immediately precedes urine is known as A. plasma |
tubular fluid. |
Glucose and amino acids are reabsorbed from the glomerular filtrate by A. the renal corpuscle. |
the proximal convoluted tubule. |
In a healthy kidney, very little ___ is filtered by the glomerulus. A. amino acids |
protein |
Which of the following would reduce the glomerular filtration rate? A. vasoconstriction of the efferent arteriole |
vasoconstriction of the afferent arteriole |
The mechanism of stabilizing the GFR based on the tendency of smooth muscle to contract when stretched is known as what? A. renal autoregulation |
the myogenic mechanism |
In response to a drop in overall blood pressure, ___ stimulates constriction of the glomerular inlet and even greater constriction of the outlet. A. azotemia |
angiotensin II |
Assuming all other values are normal, calculate the net filtration pressure in a patient with a drop in capsular hydrostatic pressure to 8 mmHg. A. 10 mm Hg out |
20 mm Hg out |
Renin hydrolyzes angiotensinogen released from the ________ to form angiotensin I. A. lungs |
liver |
Because of the great deal of active transport that occurs here, the _________ of all the nephrons collectively account for about 6% of one’s daily resting ATP and caloric consumption. A. proximal convoluted tubules |
proximal convoluted tubules |
Proximal convoluted tubules are responsible for reabsorbing all of the following except A. potassium. |
hydrogen ions. |
Total saturation of protein transporters for a given solute in the renal tubules would result in A. reabsorption of all the solute. |
appearance of that solute in the urine |
Which of the following is a direct result of antidiuretic hormone? A. decreased urine volume |
decreased urine volume |
Aldosterone acts on A. the proximal convoluted tubule. |
the distal convoluted tubule. |
Atrial natriuretic peptide reduces blood volume and pressure by all of the following means except A. increasing glomerular filtration rate. |
preventing sodium loss in the urine. |
Hypocalcemia stimulates A. a decrease in aldosterone production. |
secretion of parathyroid hormone. |
Which renal structure is responsible for producing hypertonic urine by reabsorbing water while allowing metabolic wastes and NaCl to pass through? A. glomerulus |
collecting duct |
The urine is most likely to be hypotonic when A. the body’s water volume is high. |
the body’s water volume is high. |
Which of the following does not contribute to water conservation? A. the collecting duct |
diuretics |
The countercurrent multiplier recaptures ______ and is based on fluid flowing in ______ direction in two adjacent tubules. A. potassium; the same |
sodium; the opposite |
The overall purpose of the countercurrent exchange system is A. to supply salt and urea to the renal medulla. |
to supply salt and urea to the renal medulla. |
Which of these induces renin secretion, constricts afferent arterioles, and reduces GFR, and urine volume? A. aldosterone |
norepinephrine |
Normal urine from a healthy person can be expected to contain all of the following except A. creatinine |
glucose |
What is the term for the pigment responsible for the color of urine? A. monochrome |
urochrome |
The minimum daily output of urine to meet the definition of polyuria is A. 0.5 L. |
2.0 L. |
Prior to chemical tests for glycosuria, clinicians checked for sweetness of the urine as a sign of A. diabetes insipidus. |
diabetes mellitus. |
Loop diuretics reduce body water content by acting on A. the feedback loop between the kidney and posterior pituitary gland. |
the countercurrent multiplier system. |
A hospital patient produces 4 mL/min of urine with a urea concentration of 8 mg/mL. Venous blood draw reveals urea concentration of 0.4 mg/mL. What is the percentage of cleared urea from glomerular filtrate? A. 40% |
64% |
Which two substances are most useful for determining a patient’s glomerular filtration rate? A. insulin and glucose |
inulin and creatinine |
46. Creatinine has a renal clearance of 140 mL/min due to the fact that A. it is absorbed by the loop of Henle. |
it is absorbed by the renal tubules. |
Which of the following is not found in the ureter? A. adventitia |
skeletal muscle |
Which muscle is located in the bladder? A. detrusor |
detrusor |
Which is not a portion of the urethra? A. external urethral orifice |
internal urethral sphincter |
Micturition is another term for A. the production of nitrogenous wastes. |
the elimination of urine. |
The ureters pass anterior to the bladder and enter it from below. True False |
False |
Albuminuria is a common sign of diabetes mellitus. True False |
False |
Diseases that affect the descending corticospinal tracts may limit inhibition of the sacral somatic motor neurons and thus could result in urinary incontinence. True False |
True |
Ethyl (drinking) alcohol stimulates the secretion of ADH, thereby reducing reabsorption by the collecting duct. True False |
True |
Parathyroid hormone increases phosphate excretion by the proximal convoluted tubule as well as promotes synthesis of calcitriol. True False |
True |
The countercurrent multiplier mechanism for water conservation was discovered by limiting studies to humans and thus hypothesizing how form determines function. True False |
False |
The thick segment of the nephron loop is impermeable to water. True False |
True |
Glomerular filtration occurs because glomerular oncotic pressure overrides glomerular blood pressure. True False |
False |
Angiotensin-converting enzyme is found only in the kidneys and converts angiotensinogen to angiotensin I. True False |
False |
Cells in the cleft between the afferent and efferent arterioles and among capillaries of the glomerulus are known as mesangial cells. True False |
True |
Glomerular capillaries suffer little damage from hypertension because of the protective influence of the afferent arterioles. True False |
False |
The fenestrated endothelium of the capillary has pores small enough to exclude blood cells from the filtrate. True False |
True |
The most toxic of our metabolic wastes are nitrogenous wastes. True False |
True |
Review Chapter 23
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