Chapter 14 – Cardiovascular |
blood is recirculated instead of consumed. |
2) The most accurate definition of artery is a vessel that |
transports blood away from the heart. |
3) Capillaries are best described as |
microscopic vessels in which blood exchanges material with the interstitial fluid. |
4) Which organ is NOT known to include a special portal system for blood? |
heart |
5) The purpose of having valves in the cardiovascular system is to |
ensure that blood flows in one direction. |
6) Which artery/arteries branch(es) most proximal to the beginning of the aorta at the heart? |
coronary |
7) The hepatic portal vein carries blood |
away from the digestive tract. |
8) The medical term for heart attack is |
myocardial infarction. |
9) The driving force for blood flow is |
a pressure gradient. |
10) Each of the following changes will result in increased blood flow to a tissue except one. Identify the exception. |
decreased vessel diameter |
11) Which parameters are associated with increased resistance? |
reduced flow |
12) As blood vessel length increases |
resistance increases & flow decreases. |
13) When a quantity is expressed as "4 cm/sec |
" what is being described?, the velocity of flow. |
14) The sac around the heart is the |
pericardium. |
15) The function of the pericardial fluid is to |
reduce friction between the heart and the pericardium. |
16) In the heart valves are located between the |
atria and the ventricles & between the ventricles and the arteries. |
17) Which valves have chordae tendineae? |
bicuspid and tricuspid valves & mitral valve |
18) The term myogenic indicates that the heart muscle is the |
source of the electrical signal that triggers heart contraction. |
19) The action potential in a cardiac contractile cell causes |
opening of L-type calcium channels. |
20) Stretching a myocardial cell allows |
more Ca2+ to enter & increases the force of contraction |
21) The rapid depolarization phase of the action potentials of myocardial contractile cells is due to which ion(s)? |
Na+ |
22) During the plateau phase of the action potentials of myocardial contractile cells |
which ion(s) is/are crossing the membrane?, Ca2+ & K+ |
23) The flattening of the action potentials of myocardial contractile cells |
called the plateau phase, is due to a combination of decreasing K+ permeability and increasing Ca2+ permeability. |
24) The flattening of the action potentials of myocardial contractile cells |
called the plateau phase, is due to a combination of increasing Ca2+influx and decreasing K+efflux. |
25) The end of the plateau phase is due to the |
closing of Ca2+ channels and opening of K+ channels. |
26) A typical action potential of a myocardial contractile cell lasts at least |
200 millisecond(s). |
27) The importance of the plateau phase of the action potential of myocardial cells is in |
preventing tetanus. |
28) Myocardial cells can generate action potentials spontaneously because they have |
unstable ion channels. |
29) If channels are permeable to |
Na+& K+. |
30) Epinephrine and norepinephrine increase |
ion flow through sodium and If channels. |
31) The depolarization of the pacemaker action potential spreads |
to adjacent cells through gap junctions. |
32) The fibrous skeleton of the heart is important because |
it forces electrical activity to be conducted through the atrioventricular node. |
33) The AV node is important because it |
directs electrical impulses from the atria to the ventricles & delays the transmission of the electrical impulses to the ventricles in order for the atria to finish contracting. |
34) In the condition known as complete heart block what happens? |
Electrical signals from the SA node never reach the ventricles, so the contraction of the atria is not coordinated with the contraction of the ventricles. |
35) In electrocardiography a lead is a |
pair of electrodes. |
36) When the heart is in fibrillation |
effective pumping of the ventricles ceases because the myocardial cells fail to work as a team, and the brain cannot get adequate oxygen. |
37) Electrical shock to the heart is usually used to treat |
ventricular fibrillation. |
38) A heart rate of 125 beats per minute could be correctly termed |
tachycardia. |
39) Which event happens at the start of a cardiac cycle? |
The SA node fires. |
40) Which of the following events result in the first heart sound? |
The AV valves close. |
41) During the isovolumic phase of ventricular systole |
the atrioventricular valves and semilunar valves are closed. |
42) During the cardiac cycle |
the QRS complex of the ECG precedes the increase in ventricular pressure. |
43) The volume of blood ejected from each ventricle during a contraction is called the |
stroke volume. |
44) The cardiac output is equal to the product of |
heart rate and stroke volume. |
45) During ventricular systole |
the AV valves are closed. |
46) According to Starling’s law of the heart |
the cardiac output is directly related to the venous return. |
47) Drugs known as beta-blockers will |
decrease heart rate. |
48) In order for blood to enter the heart |
the atria must be in diastole & the pressure in the atria must be lower than in the veins. |
49) The term used to describe the amount of blood in the ventricle available to be pumped out of the heart during the next contraction is |
end-diastolic volume (EDV). |
50) The term that describes the volume of blood circulated by the heart in one minute is |
cardiac output (CO). |
51) During ventricular ejection |
the ventricles are in systole. |
52) Which of these will increase the heart rate? |
Sympathetic stimulation to the SA node & the application of epinephrine to the SA node |
53) At an intercalated disc |
two cardiac muscle cells are connected by gap junctions. |
54) Stimulation of the beta receptors on heart muscle results in the formation of |
cAMP. |
55) Which of the following statements about hydrostatic pressure is NOT true? |
If a fluid is not moving the pressure that it exerts is called hydrostatic pressure & The lateral component of moving fluid represents the hydrostatic pressure. |
56) Which of the following will increase flow in a vessel the most? |
Increase radius by 1 unit. |
57) Autorhythmic cells are also called pacemakers because they |
set the rate of the heartbeat. |
58) ECGs provide indirect information about the heart function and show |
the summed electrical potentials generated by all cells of the heart. |
59) The P wave of an ECG corresponds to the |
depolarization of the atria. |
60) The QRS complex of an ECG corresponds to the |
progressive wave of ventricular depolarization. |
61) Ventricular contraction begins |
just after the Q wave. |
62) Atrial contraction begins during |
the latter part of the P wave. |
63) QRS complex : |
Immediately followed by ventricular contraction |
64) PR segment : |
atrial contraction |
65) T wave: |
ventricular repolarization |
66) QRS complex: |
ventricular depolarization |
67) P wave: |
atrial depolarization |
68) cardiac output (CO): |
the volume of blood circulated by the heart in one minute |
69) stroke volume (SV): |
the amount of blood pumped out of the heart during one contraction |
70) end-systolic volume (ESV): |
the amount of blood left in the ventricle after it contracts |
71) end-diastolic volume (EDV): |
the amount of blood in the ventricle available to be pumped out of the heart during one contraction terms: |
72) tricuspid valve: |
an AV valve that has three flaps |
73) pulmonary valve: |
a semilunar valve that has the right ventricle on one side |
74) bicuspid valve: |
also called the mitral valve |
75) aortic valve: |
has three cup like leaflets and has the aorta on one side |
76) The chambers of the heart that pump blood into the arteries are the |
ventricles. |
77) The chambers of the heart that receive blood from the veins are the |
atria. |
78) The most proximal arteries to branch from the aorta are the |
coronary arteries. |
79) An increase in blood vessel diameter is known as |
vasodilation. |
80) The contraction phase of the cardiac cycle is termed |
systole. |
81) A resting heart rate of less than 60 beats per minute is identified as |
bradycardia. |
82) A resting heart rate above 100 beats per minute is identified as |
tachycardia. |
83) A heart with cells contracting rapidly in a disorganized manner with no effective pumping action, is said to be in |
fibrillation |
84) A tracing of the electrical activity of the heart monitored by electrodes placed on the skin, is called an |
electrocardiogram |
85) The period of time from the beginning of one heartbeat to the beginning of the next is termed the |
cardiac cycle. |
86) The period when blood is pushed into the arteries is called |
ventricular ejection. |
87) Narrowing of the opening of a heart valve is referred to as |
stenosis. |
88) Listening to the heart through the chest wall is called |
auscultation. |
89) The rule that states "Within limits the heart pumps all of the blood that returns to it" is known as the |
Frank-Starling Law of the Heart. |
90) The pulmonary circuit carries blood to and from the |
alveoli of the lungs. |
91) The systemic circuit carries blood to and from all parts of the body except the |
alveoli of the lungs. |
92) Arteries are blood vessels that carry blood |
away from the heart. |
93) Veins are blood vessels that carry blood |
toward the heart. |
94) The heart is enclosed in the |
pericardial membrane. |
95) The superior portion of the heart where the major blood vessels enter and exit is the |
base. |
96) The inferior point of the heart is called the |
apex. |
97) The septum is a wall that |
separates the two sides of the heart. |
98) The muscle layer of the heart wall is the |
myocardium. |
99) The cells responsible for establishing the rate of a cardiac contraction are the |
nodal cells. |
100) Abnormal patterns of cardiac activity are known as |
arrhythmias. |
101) The end-diastolic volume is the amount of blood in a ventricle at the beginning of |
systole. |
102) The end-diastolic volume is the amount of blood in a ventricle after it has contracted and before it begins to |
refill. |
103) The amount of blood returning to the heart is the |
venous return. |
104) The term for reduced blood flow to the cardiac muscle is |
coronary ischemia. |
105) The primary function of the cardiovascular system is to |
transport material to and from all parts of the body. |
106) The cardiovascular system is made up of the |
heart, blood vessels and blood. |
107) Name the three portal systems in the body. |
1. hepatic portal system 2. renal portal system 3. hypothalamic-hypophyseal portal system |
108) The pressure created in the ventricles is called the driving pressure because |
it is the force that drives blood through the blood vessels |
109) The heart is encased in a tough membranous sac called the prticardium and is composed mostly of cardiac muscle tissue |
called the myocardium |
110) The pulmonary trunk directs blood from the right ventricle of the heart to the lungs. Backflow of blood to the heart is prevented by pulmonary valve. Blood from the lungs returns blood to the heart via pulmonary veins. |
… |
111) The opening between each atrium and its ventricle is guarded by the atrioventricular valve |
which connect the ventricular side to collagenous tendons, called chordae tendineae. Papillary muscles provide stability for these tendons. |
112) Cell junctions in contractile cells are called intercalated disks |
which consist of two components: desmosomes and gap junctions. |
113) The ryanodine receptors are calcium channels in cardiac contractile cells. |
Opening them causes calcium-induced calcium release. |
114) The AV node delays the transmission of action potentials slightly to allow the atria to complete their contraction before |
ventricular contraction begins. |
115) Place these structures in the order that blood returning to the heart from the body would pass through them. |
right atrium right ventricle pulmonary artery pulmonary vein left atrium left ventricle |
116) Put these autorhythmic cells into the correct order for conveying electrical signals through a normal heart. |
sinoatrial nodes internodal pathway atrioventricular node bundle of His left and right bundle branches Purkinje fibers |
117) Left ventricular pressure is higher than pressure in the aorta during |
ventricular diastole. |
118) Abnormally slow conduction through the ventricles would change the |
QRS complex in an ECG tracing. |
119) A certain drug decreases heart rate by producing hyperpolarization in the pacemaker cells of the heart. |
This drug probably binds to muscarinic receptors. |
120) Under which set of circumstances would the diameter of peripheral blood vessels be the greatest? |
decreased sympathetic stimulation |
121) Acetylcholine slows the heart rate by increasing the permeability to |
K+ and decreasing the permeability to Ca2+. |
122) Sympathetic stimulation increases the heart rate by |
increasing ion influx thus increasing the rate of depolarization. |
123) Which statement is NOT true regarding cardiac muscle? |
Cardiac muscle cells must obey the all-or-none law of contraction. |
124) Put these phases of the cardiac cycle in the correct order. |
beginning of atrial systole completion of ventricular filling beginning of ventricular systole closure of the AV valves isovolumic contraction opening of the semilunar valves ventricular ejection ventricular relaxation |
125) As a result of the long refractory period |
cardiac muscle cannot exhibit tetany. |
126) Drugs known as calcium channel blockers can be used to |
decrease the force of cardiac contraction. |
127) If the membranes of the cardiac muscle cells in the SA node become more permeable to potassium ions |
the heart rate will decrease. |
128) The ECG of a person suffering from complete heart block would show |
more P waves than QRS complexes per minute. |
129) If blood pressure doubled at the same time that the peripheral resistance doubled |
the blood flow through a vessel would be unchanged. |
130) Which of the following conditions would have the greatest effect on peripheral resistance? |
doubling the diameter of a vessel |
131) If the connection between the AV node and bundle of His becomes blocked |
the ventricles will beat more slowly. |
132) If a myocardial infarction results in the formation of scar tissue along the pathway of the left bundle branch |
cardiac arrhythmias may occur. |
133) Manganese ions block the calcium channels in the cardiac muscle membrane. How would the presence of manganese in the extracellular fluid affect the contraction of the heart muscle? |
The heart would beat less forcefully. |
134) If there is a blockage between the AV node and the AV bundle |
how will this affect the appearance of the electrocardiogram? There will be more P waves than QRS complexes. |
135) In which of the following situations would the end-systolic volume (ESV) be the greatest? |
when parasympathetic stimulation of the heart is increased |
136) In which situation would the stroke volume be the greatest? |
when venous return is increased |
137) If the EDV is 140 mL which other values are most likely to occur in a healthy, normal person? |
The ESV could be 70 mL and the SV could be 70 mL and The ESV could be 50 mL and the SV could be 90 mL. |
138) The blood pressure in a vessel is 10 units at point A and 10 units at point B. |
Flow between those points is stopped. |
139) The blood pressure in a vessel is 20 units at point A and 10 units at point B. One minute later the pressure is 15 units at point A and five units at point B. |
Flow between those points is unchanged |
140) Joey develops a medical condition that decreases his blood viscosity. Assuming no other change (e.g.no compensatory reflex), what happens to his blood pressure? |
decreased |
141) When a blood vessel dilates |
resistance through that vessel is decreased. |
142) When a blood vessel dilates |
blood viscosity is unchanged. |
143) When a blood vessel dilates |
velocity of blood is decreased. |
144) You suck milk through a 6-inch straw and through a 10-inch straw; the diameters are identical. |
Resistance is increased in the 10-inch straw compared to the 6-inch straw. |
145) Blood pressure decreases during sleep. How does this affect velocity? |
decreased. |
146) During fasting some capillary beds in the digestive tract are closed and therefore have no blood flow. Others are open to meet the minimal need of the tract for blood flow. During eating and as long as food is present in the tract, all capillary beds open to flow. What happens to total cross-sectional area of vessels in the digestive tract? |
increased |
147) If total cross-sectional area of blood vessels in an organ increases what happens to velocity of blood through that organ? |
decreased |
148) If total cross-sectional area of vessels in an organ remains the same but blood flow to that organ increases, what happens to velocity of blood? |
increased. |
149) The resting membrane potential is -70 mV for skeletal muscle and -90 mV for contractile myocardium. |
It is an unstable pacemaker potential (usually starts at -60 mV) for autorhythmic myocardium. |
150) The rising phase of the action potential is a result of |
Na+ entry for skeletal muscle, Na+ entry for contractile myocardium, and calcium entry for autorhythmic myocardium. |
151) The duration of the action potential is extended: 200+ msec |
… |
152) In the autorhythmic cellsthe If channels open when the cell membrane potential is -60 mV. |
These channels are permeable to K+ and Na+. |
153) Sympathetic stimulation to the pacemaker cells increases heart rate by |
increasing ion flow through If and calcium channels. |
Chapter 14 Cardiovascular Physiology
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