What was the main goal of the Human Genome Project (HGP)? |
to map all the human genes and determine the nucleotide sequence of the entire human genome |
BLAST is a computational tool used by genome biologists to _____. |
compare a given DNA or protein sequence to all other DNA or protein sequences in a database |
Which of the following statements about genome sizes is true? |
Most eukaryotes have larger genomes than most prokaryotes. |
The number of genes correlates with _____. |
the size of the genome in prokaryotes |
What type of noncoding DNA comprises the largest portion of multicellular eukaryotic genomes? |
transposons |
How do retrotransposons differ from other transposons? |
Retrotransposons move via an RNA transcript, whereas other transposons do not. |
How has gene duplication played a critical role in evolution? |
It produces redundant copies of existing genes, which are then free to mutate and adopt new functions. |
By what mechanism might transposons contribute to gene duplication? |
Transposons may promote unequal crossing over during meiosis. |
What is the goal of comparative genomic studies? |
to identify homologues in model organisms for genes involved in human disease, to identify genes that are important for evolution of a particular species, to study how genomes evolve, to study genetic variation within a species or a population |
What are Hox genes? |
Hox genes encode transcription factors with a DNA-binding domain called a homeo box, and regulate development of the vertebrate body plan. |
For mapping studies of genomes, most of which were far along before 2000, the three-stage method was often used. Which of the following is the usual order in which the stages were performed, assuming some overlap of the three? |
linkage map, physical map, sequencing of fragments |
Several of the different globin genes are expressed in humans, but at different times in development. What mechanism could allow for this? |
differential gene regulation over time |
Biology 1201-Ch.21 Quiz
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